Human coronavirus 229E

Human coronavirus 229E; (HCoV-229E)
Videnskabelig klassifikation
Domæne	Riboviria
Rige	Orthornavirae
Række	Pisuviricota
Klasse	Pisoniviricetes
Orden	Nidovirales
Familie	Coronaviridae
Slægt	Alphacoronavirus
Underslægt	Duvinacovirus
Art	Human coronavirus 229E
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Human coronavirus 229E ('HCoV-229E') er en art af coronavirus, der inficerer mennesker og flagermus.^[1] Det er en indkapslet, enkeltstrenget (single-stranded) RNA-virus med positiv sense, der trænger ind i værtscellen ved at binde til APN-receptoren (aminopeptidase N).^[2] Sammen med Human coronavirus OC43 (et medlem af Betacoronavirus-slægten) er det en af de virus, der er ansvarlig for forkølelse.^[3]^[4] HCoV-229E er medlem af slægten Alphacoronavirus og underslægten Duvinacovirus.^[5]^[6]

Referencer[redigér | rediger kildetekst]

^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). "Human Coronaviruses: A Review of Virus–Host Interactions". Diseases. 4 (3): 26. doi:10.3390/diseases4030026. ISSN 2079-9721. PMC 5456285. PMID 28933406. See Table 1.
^ Fehr AR, Perlman S (2015). Maier HJ, Bickerton E, Britton P (red.). "Coronaviruses: an overview of their replication and pathogenesis". Methods in Molecular Biology. Springer. 1282: 1-23. doi:10.1007/978-1-4939-2438-7_1. ISBN 978-1-4939-2438-7. PMC 4369385. PMID 25720466. See Table 1. − "...Many α-coronaviruses utilize aminopeptidase N (APN) as their receptor, ..."
^ Susanna K. P. Lau, Paul Lee, Alan K. L. Tsang, Cyril C. Y. Yip,1 Herman Tse, Rodney A. Lee, Lok-Yee So, Yu-Lung Lau, Kwok-Hung Chan, Patrick C. Y. Woo, and Kwok-Yung Yuen. Molecular Epidemiology of Human Coronavirus OC43 Reveals Evolution of Different Genotypes over Time and Recent Emergence of a Novel Genotype due to Natural Recombination. J Virology. 2011 November; 85(21): 11325–11337.
^ E. R. Gaunt,1 A. Hardie,2 E. C. J. Claas,3 P. Simmonds,1 and K. E. Templeton. Epidemiology and Clinical Presentations of the Four Human Coronaviruses 229E, HKU1, NL63, and OC43 Detected over 3 Years Using a Novel Multiplex Real-Time PCR Method down-pointing small open triangle. J Clin Microbiol. 2010 August; 48(8): 2940–2947.
^ "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV) (engelsk). oktober 2018. Hentet 13. januar 2019.
^ Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804-1820. doi:10.3390/v2081803. ISSN 1999-4915. PMC 3185738. PMID 21994708. Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein.